ANKMY2

Across TCGA patient cohorts, ANKMY2 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKMY2-associated genes across cancer lineages are EGFR_pY1068, PDCD4, and ATM. Each is linked with ANKMY2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKMY2-to-partner and partner-to-ANKMY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by ANKMY2-low versus ANKMY2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKMY2→partner) and Y-score (partner→ANKMY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.266	-2.999	.018	.035	3	3
UCEC	PDCD4 →	-0.523	-3.169	.013	.018	3	2
UCEC	ATM →	-0.521	-2.000	.010	.032	3	2
UCEC	Caspase-7-cleavedD198 →	+0.752	+3.479	.004	.002	3	2
UCEC	c-Met_pY1235 →	+0.085	+3.469	.011	.002	3	2
UCEC	4E-BP1 →	+0.304	+3.029	.012	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

EGFR_pY1068 by ANKMY2 expression — UCEC

Explore this box plot interactively →