ANKMY2

Across TCGA cell cohorts, ANKMY2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKMY2-associated genes across cancer lineages are NT5C1A, ESX1, and ZNF831. Each is linked with ANKMY2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKMY2-to-partner and partner-to-ANKMY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NT5C1A grouped by ANKMY2-low versus ANKMY2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKMY2→partner) and Y-score (partner→ANKMY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NT5C1A →	+0.054	+4.684	<.001	.002	3	1
LARGE_INTESTINE	ESX1 →	+0.041	+4.467	<.001	.004	3	1
LARGE_INTESTINE	ZNF831 →	+0.018	+4.273	<.001	.006	3	1
LARGE_INTESTINE	MSGN1 →	+0.134	+4.930	<.001	.001	3	1
LARGE_INTESTINE	TAFA1 →	+0.410	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR4A47 →	+0.022	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

NT5C1A by ANKMY2 expression — LARGE_INTESTINE

Explore this box plot interactively →