ANKMY1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKMY1 mutation is significantly associated with the RNA expression of many other genes, with 4,608 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKMY1-associated genes across cancer lineages are BCCIP, INPP1, and MCMBP. Each is linked with ANKMY1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ANKMY1-to-partner and partner-to-ANKMY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCCIP grouped by ANKMY1-low versus ANKMY1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKMY1→partner) and Y-score (partner→ANKMY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBCCIP →+0.314+1.358.003.00435
HNSCINPP1 →+1.027+3.356<.001.00534
UCECMCMBP →+0.343+1.589.005.00134
UCECEI24 →+0.396+1.736<.001<.00134
UCECZNF367 →+0.772+1.954<.001<.00134
STADING2 →+0.447+3.597.002.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,608 associations by consensus.

BCCIP by ANKMY1 expression — UCEC

Box plot of BCCIP in ANKMY1-low vs ANKMY1-high samples in UCEC.

Explore this box plot interactively →

Exploration