ANKLE1

Across TCGA patient cohorts, ANKLE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,104 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANKLE1-associated proteins across cancer lineages are USP39, BRD4, and DDX39A. Each is linked with ANKLE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ANKLE1-to-partner and partner-to-ANKLE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKLE1 versus USP39 in UCEC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKLE1→partner) and Y-score (partner→ANKLE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	USP39 →	+0.285	+0.818	<.001	<.001	3	5
BRCA	BRD4 →	+0.346	+0.966	<.001	<.001	3	5
UCEC	DDX39A →	+0.477	+0.717	<.001	.001	3	5
BRCA	FGGY →	-0.374	-0.843	.001	<.001	3	5
UCEC	AKAP8L →	+0.334	+0.673	<.001	.001	3	5
LSCC	AQR →	+0.330	+0.692	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,104 associations by consensus.

ANKLE1 vs USP39 — UCEC

Explore this scatter interactively →