ANKK1

Across TCGA patient cohorts, ANKK1 mutation is significantly associated with the RNA expression of many other genes, with 2,956 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKK1-associated genes across cancer lineages are SNW1, DNAJC17, and FOXRED1. Each is linked with ANKK1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKK1-to-partner and partner-to-ANKK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNW1 grouped by ANKK1-low versus ANKK1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKK1→partner) and Y-score (partner→ANKK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNW1 →	+0.403	+2.858	.002	.001	3	3
SKCM	DNAJC17 →	+0.334	+2.647	<.001	.004	3	3
SKCM	FOXRED1 →	+0.380	+3.647	.003	.001	2	4
SKCM	RRP9 →	+0.457	+3.973	<.001	<.001	3	3
SKCM	XRCC3 →	+0.503	+2.254	<.001	.001	3	3
UCEC	HIRIP3 →	+0.386	+2.010	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,956 associations by consensus.

SNW1 by ANKK1 expression — SKCM

Explore this box plot interactively →