ANKK1

Across TCGA cell cohorts, ANKK1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ANKK1-associated genes across cancer lineages are RBMY1A1, CCDC178, and OTUD6A. Each is linked with ANKK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKK1-to-partner and partner-to-ANKK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1A1 grouped by ANKK1-low versus ANKK1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKK1→partner) and Y-score (partner→ANKK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	RBMY1A1 →	+0.029	+5.209	<.001	.005	3	2
STOMACH	CCDC178 →	+0.527	+3.688	.009	.007	3	1
STOMACH	OTUD6A →	+0.015	+3.432	<.001	.008	3	1
STOMACH	TRIM49C →	+0.021	+3.794	<.001	.003	3	1
LUNG_NSCLC_LUAD	CDCP2 →	+0.020	+4.347	.001	.001	3	1
LARGE_INTESTINE	TMSB4Y →	+0.946	+3.374	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

RBMY1A1 by ANKK1 expression — BLOOD_Lymphoma

Explore this box plot interactively →