ANKIB1

Across TCGA cell cohorts, ANKIB1 mutation is significantly associated with the RNA expression of many other genes, with 685 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKIB1-associated genes across cancer lineages are TRIML1, OR56A5, and ICMT. Each is linked with ANKIB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKIB1-to-partner and partner-to-ANKIB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIML1 grouped by ANKIB1-low versus ANKIB1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKIB1→partner) and Y-score (partner→ANKIB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TRIML1 →	+0.071	+3.786	.006	.001	3	2
UPPER_AERODIGESTIVE_TRACT	OR56A5 →	+0.045	+4.736	<.001	.009	3	2
LARGE_INTESTINE	ICMT →	+0.535	+2.502	.006	.005	3	2
LARGE_INTESTINE	AUNIP →	+0.488	+3.234	.004	.004	3	2
LARGE_INTESTINE	MTX2 →	+0.291	+3.064	.009	.009	3	2
LARGE_INTESTINE	NUP54 →	+0.464	+2.502	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 685 associations by consensus.

TRIML1 by ANKIB1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →