ANKHD1

Across TCGA patient cohorts, ANKHD1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,732 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ANKHD1-associated genes across cancer lineages are TSPYL1, PITX1, and DNAJC12. Each is linked with ANKHD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKHD1-to-partner and partner-to-ANKHD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKHD1 versus TSPYL1 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKHD1→partner) and Y-score (partner→ANKHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TSPYL1 →	-0.509	-0.257	<.001	.006	3	3
BRCA	PITX1 →	+1.002	+0.227	.008	.002	3	3
BRCA	DNAJC12 →	-1.762	-0.333	.001	<.001	3	3
CCRCC	WDR55 →	+0.352	+0.326	<.001	<.001	3	3
GBM	EHD3 →	-0.794	-0.361	.002	<.001	3	2
BRCA	ISCU →	-0.471	-0.369	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,732 associations by consensus.

ANKHD1 vs TSPYL1 — GBM

Explore this scatter interactively →