ANKHD1

Across TCGA cell cohorts, ANKHD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,443 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANKHD1-associated GO terms across cancer lineages are Protein polyubiquitination, Establishment of protein localization to organelle, and Viral translational termination-reinitiation. Each is linked with ANKHD1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ANKHD1-to-partner and partner-to-ANKHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by ANKHD1-low versus ANKHD1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKHD1→partner) and Y-score (partner→ANKHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein polyubiquitination →	+0.056	+0.853	<.001	<.001	3	16
OESOPHAGUS	Establishment of protein localization to organelle →	+0.069	+0.815	<.001	.003	3	16
BONE	Viral translational termination-reinitiation →	+0.082	+0.969	<.001	<.001	3	16
BONE	Subtelomeric heterochromatin formation →	+0.163	+0.917	<.001	<.001	3	16
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.175	+0.946	.009	.001	3	16
LARGE_INTESTINE	Epigenetic regulation of gene expression →	+0.061	+0.869	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,443 associations by consensus.

Protein polyubiquitination by ANKHD1 expression — OESOPHAGUS

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