ANKHD1

Across TCGA cell cohorts, ANKHD1 mutation is significantly associated with the mutation status of many other genes, with 3,638 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKHD1-associated genes across cancer lineages are CTTNBP2, SATB2, and SUPT6H. Each is linked with ANKHD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANKHD1-to-partner and partner-to-ANKHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTTNBP2 grouped by ANKHD1-low versus ANKHD1-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKHD1→partner) and Y-score (partner→ANKHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	CTTNBP2 →	+5.437	+5.437	.003	.003	1	6
OVARY	SATB2 →	+4.510	+3.047	.001	.001	1	6
CNS	SUPT6H →	+4.277	+4.584	.001	.001	1	6
OVARY	OBSL1 →	+3.510	+2.760	.003	.003	1	6
BREAST	UBR4 →	+3.857	+4.807	.002	.002	1	6
LARGE_INTESTINE	PCM1 →	+1.862	+2.479	.001	.001	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,638 associations by consensus.

CTTNBP2 by ANKHD1 expression — BONE

Explore this box plot interactively →