Across TCGA patient cohorts, ANKFY1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,964 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANKFY1-associated proteins across cancer lineages are YWHAE, MANF, and TTC19. Each is linked with ANKFY1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANKFY1-to-partner and partner-to-ANKFY1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKFY1→partner) and Y-score (partner→ANKFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YWHAE →	+0.288	+0.465	<.001	<.001	3	6
LSCC	MANF →	-0.432	-0.377	.002	.002	3	5
HNSC	TTC19 →	+0.266	+0.488	.003	.004	3	5
GBM	SPAG7 →	+0.312	+0.434	<.001	<.001	3	5
BRCA	RPA1 →	+0.304	+0.557	<.001	<.001	3	4
BRCA	MAP2K4 →	+0.457	+0.557	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,964 associations by consensus.

Exploration

ANKFY1 survival (RNA) · tumor vs normal (RNA) · all ANKFY1 data types