Across TCGA patient cohorts, ANKFY1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,269 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANKFY1-associated genes across cancer lineages are PAFAH1B1, JAM2, and STX8. Each is linked with ANKFY1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANKFY1-to-partner and partner-to-ANKFY1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKFY1→partner) and Y-score (partner→ANKFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PAFAH1B1 →	+0.608	+0.208	.001	.008	3	8
GBM	JAM2 →	+0.791	+0.244	<.001	.001	3	7
OV	STX8 →	+0.464	+0.194	<.001	<.001	3	7
BRCA	ARHGEF6 →	+0.577	+0.121	<.001	.002	3	7
LSCC	ST3GAL5 →	+0.566	+0.230	<.001	<.001	3	6
OV	UBE2G1 →	+0.575	+0.289	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,269 associations by consensus.

Exploration

ANKFY1 survival (RNA) · tumor vs normal (RNA) · all ANKFY1 data types