Across TCGA patient cohorts, ANKFY1 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKFY1-associated genes across cancer lineages are ATM, Cyclin-E2, and INPP4B. Each is linked with ANKFY1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKFY1-to-partner and partner-to-ANKFY1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKFY1→partner) and Y-score (partner→ANKFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.497	-2.662	<.001	<.001	3	4
UCEC	Cyclin-E2 →	+0.140	+1.935	.005	.002	3	4
UCEC	INPP4B →	-0.235	-2.070	.016	.001	3	2
UCEC	JNK_pT183_Y185 →	-0.195	-3.087	<.001	<.001	3	2
UCEC	mTOR_pS2448 →	-0.126	-1.986	.005	.008	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.417	-1.517	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

ANKFY1 survival (RNA) · tumor vs normal (RNA) · all ANKFY1 data types