ANKFY1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKFY1 mutation is significantly associated with the RNA expression of many other genes, with 156 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKFY1-associated genes across cancer lineages are CCL16, KRTAP4-4, and C20orf141. Each is linked with ANKFY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKFY1-to-partner and partner-to-ANKFY1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKFY1→partner) and Y-score (partner→ANKFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTCCL16 →+0.010+4.087<.001.00931
BLOOD_MyelomaKRTAP4-4 →+0.030+4.807<.001.00631
BLOOD_MyelomaC20orf141 →+0.106+4.807<.001.00631
BLOOD_LeukemiaSLC32A1 →+0.411+2.638.003.00931
BLOOD_LeukemiaGZMK →+0.463+3.622<.001<.00131
BLOOD_LeukemiaMARK1 →+0.848+3.534<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 156 associations by consensus.

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