ANKFN1

Across TCGA patient cohorts, ANKFN1 mutation is significantly associated with the RNA expression of many other genes, with 2,080 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKFN1-associated genes across cancer lineages are RAD51, MSANTD3, and SETD3. Each is linked with ANKFN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKFN1-to-partner and partner-to-ANKFN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by ANKFN1-low versus ANKFN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKFN1→partner) and Y-score (partner→ANKFN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD51 →	+0.732	+1.949	<.001	.001	3	3
UCEC	MSANTD3 →	+0.517	+1.949	<.001	.001	3	3
UCEC	SETD3 →	+0.389	+2.828	<.001	.001	3	3
UCEC	POLH-AS1 →	+0.554	+2.119	<.001	.002	3	3
UCEC	CMC2 →	+0.434	+1.938	<.001	.001	3	3
UCEC	OIP5 →	+0.608	+1.960	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,080 associations by consensus.

RAD51 by ANKFN1 expression — UCEC

Explore this box plot interactively →