ANKFN1

Across TCGA cell cohorts, ANKFN1 mutation is significantly associated with the RNA expression of many other genes, with 184 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKFN1-associated genes across cancer lineages are TBATA, SULT2A1, and HPGDS. Each is linked with ANKFN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKFN1-to-partner and partner-to-ANKFN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBATA grouped by ANKFN1-low versus ANKFN1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKFN1→partner) and Y-score (partner→ANKFN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	TBATA →	+0.154	+3.700	<.001	.005	3	1
CNS	SULT2A1 →	+0.053	+4.321	<.001	.002	3	1
CNS	HPGDS →	+0.044	+4.047	.001	.004	3	1
CNS	GYPA →	+0.105	+3.774	<.001	.008	3	1
CNS	PRORY →	+0.466	+4.044	.002	.003	3	1
LUNG_SCLC	IGLL1 →	+0.110	+2.884	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

TBATA by ANKFN1 expression — OVARY

Explore this box plot interactively →