ANKDD1A

Across TCGA patient cohorts, ANKDD1A mutation is significantly associated with the RNA expression of many other genes, with 1,028 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKDD1A-associated genes across cancer lineages are PKN3, ATMIN, and GDE1. Each is linked with ANKDD1A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKDD1A-to-partner and partner-to-ANKDD1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PKN3 grouped by ANKDD1A-low versus ANKDD1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKDD1A→partner) and Y-score (partner→ANKDD1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PKN3 →	+0.643	+2.700	<.001	.006	3	2
UCEC	ATMIN →	+0.403	+2.202	.007	.001	3	2
UCEC	GDE1 →	+0.377	+2.169	.008	.003	3	2
UCEC	GTSE1 →	+0.738	+3.595	<.001	.001	3	2
UCEC	WDR76 →	+0.692	+2.191	<.001	.002	3	2
READ	RNA5SP19 →	+0.972	+5.039	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,028 associations by consensus.

PKN3 by ANKDD1A expression — UCEC

Explore this box plot interactively →