ANK3

Across TCGA patient cohorts, ANK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,743 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANK3-associated proteins across cancer lineages are ANK3_S1459, ANK3_S4229, and ANK3_S4342. Each is linked with ANK3 in more than 8 cancer types. Because this analysis shows association rather than direction, both ANK3-to-partner and partner-to-ANK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANK3 versus ANK3_S1459 in LUAD, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANK3→partner) and Y-score (partner→ANK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ANK3_S1459 →	+1.249	+0.872	<.001	<.001	3	9
GBM	ANK3_S4229 →	+0.797	+1.327	<.001	<.001	3	8
LUAD	ANK3_S4342 →	+1.776	+1.742	<.001	<.001	3	8
BRCA	ANK3_S959 →	+0.887	+1.053	.008	<.001	2	9
HNSC	ADD3 →	+0.332	+0.640	<.001	<.001	3	7
LUAD	ANK3_S4298 →	+1.070	+0.955	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,743 associations by consensus.

ANK3 vs ANK3_S1459 — LUAD

Explore this scatter interactively →