ANK3

Across TCGA patient cohorts, ANK3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,976 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ANK3-associated genes across cancer lineages are ARL4AP1, CCN4, and INHBA. Each is linked with ANK3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ANK3-to-partner and partner-to-ANK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANK3 versus ARL4AP1 in LUAD, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANK3→partner) and Y-score (partner→ANK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ARL4AP1 →	+1.033	+0.551	<.001	<.001	3	7
OV	CCN4 →	-1.809	-0.666	<.001	<.001	3	6
OV	INHBA →	-1.485	-0.432	<.001	<.001	3	6
OV	MMP19 →	-1.460	-0.625	<.001	<.001	3	6
OV	ANK3-DT →	+0.982	+0.645	<.001	<.001	3	6
LSCC	LINC01050 →	-0.970	-0.274	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,976 associations by consensus.

ANK3 vs ARL4AP1 — LUAD

Explore this scatter interactively →