ANK3

Across TCGA cell cohorts, ANK3 mutation is significantly associated with the RNA expression of many other genes, with 1,681 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANK3-associated genes across cancer lineages are PABPC5, ZSWIM7, and RHBDD3. Each is linked with ANK3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANK3-to-partner and partner-to-ANK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PABPC5 grouped by ANK3-low versus ANK3-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANK3→partner) and Y-score (partner→ANK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PABPC5 →	+0.106	+3.222	.007	.006	3	3
STOMACH	ZSWIM7 →	+0.638	+2.944	.006	.007	3	3
LARGE_INTESTINE	RHBDD3 →	+0.605	+1.265	.005	.003	3	3
LARGE_INTESTINE	BCAS2 →	+0.490	+1.386	<.001	.007	3	3
LARGE_INTESTINE	ZNHIT6 →	+0.429	+1.616	.002	.005	3	3
LARGE_INTESTINE	BBOF1 →	+0.522	+1.265	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,681 associations by consensus.

PABPC5 by ANK3 expression — PANCREAS

Explore this box plot interactively →