ANK1

Across TCGA patient cohorts, ANK1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,322 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANK1-associated genes across cancer lineages are HBA2, HBA1, and HBB. Each is linked with ANK1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ANK1-to-partner and partner-to-ANK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANK1 versus HBA2 in PDAC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANK1→partner) and Y-score (partner→ANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HBA2 →	+2.499	+0.904	<.001	<.001	3	10
GBM	HBA1 →	+1.874	+0.924	<.001	<.001	3	10
PDAC	HBB →	+2.757	+0.863	<.001	<.001	3	10
GBM	PPBP →	+1.290	+0.722	<.001	<.001	3	7
GBM	DUSP1 →	+1.286	+0.865	<.001	<.001	3	6
OV	ZFP36 →	+1.548	+1.097	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,322 associations by consensus.

ANK1 vs HBA2 — PDAC

Explore this scatter interactively →