ANGPTL7

Across TCGA patient cohorts, ANGPTL7 protein abundance is significantly associated with the RNA expression of many other genes, with 251 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANGPTL7-associated genes across cancer lineages are APOL4, FASLG, and UBASH3B. Each is linked with ANGPTL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANGPTL7-to-partner and partner-to-ANGPTL7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANGPTL7 versus APOL4 in HNSC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPTL7→partner) and Y-score (partner→ANGPTL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	APOL4 →	+1.219	+0.664	<.001	.003	3	1
HNSC	FASLG →	+1.517	+0.726	.005	.003	3	1
HNSC	UBASH3B →	+0.715	+0.714	.004	.007	3	1
HNSC	GIMAP5 →	+0.920	+0.759	.006	.008	3	1
HNSC	MIR183 →	-0.947	-0.898	.004	.004	3	1
HNSC	TRBV7-3 →	+1.029	+0.829	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 251 associations by consensus.

ANGPTL7 vs APOL4 — HNSC

Explore this scatter interactively →