ANGPTL7

Across TCGA cell cohorts, ANGPTL7 RNA expression is significantly associated with the go_rna of many other GO terms, with 701 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ANGPTL7-associated GO terms across cancer lineages are mRNA transport, Regulation of double-strand break repair via homologous recombination, and Epigenetic regulation of gene expression. Each is linked with ANGPTL7 in more than 4 cancer types. Because this analysis shows association rather than direction, both ANGPTL7-to-partner and partner-to-ANGPTL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA transport grouped by ANGPTL7-low versus ANGPTL7-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPTL7→partner) and Y-score (partner→ANGPTL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	mRNA transport →	+0.050	+0.030	.004	.005	2	5
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair via homologous recombination →	+0.046	+0.038	.003	.005	3	4
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.042	+0.038	<.001	.005	3	4
SKIN	Phosphatidylethanolamine metabolic process →	+0.086	+0.580	.002	.007	2	5
UPPER_AERODIGESTIVE_TRACT	Microtubule polymerization →	+0.077	+0.028	.001	.007	2	4
UPPER_AERODIGESTIVE_TRACT	Histone mRNA catabolic process →	+0.053	+0.037	.006	.006	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 701 associations by consensus.

mRNA transport by ANGPTL7 expression — BLOOD_Lymphoma

Explore this box plot interactively →