ANGPTL6

Across TCGA patient cohorts, ANGPTL6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,647 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANGPTL6-associated proteins across cancer lineages are DOCK2, FYB1, and IL16. Each is linked with ANGPTL6 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANGPTL6-to-partner and partner-to-ANGPTL6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANGPTL6 versus DOCK2 in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPTL6→partner) and Y-score (partner→ANGPTL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DOCK2 →	+0.720	+0.451	<.001	<.001	3	8
LSCC	FYB1 →	+0.690	+0.412	<.001	<.001	3	8
LSCC	IL16 →	+0.803	+0.441	<.001	<.001	3	8
HNSC	ITGAL →	+0.632	+0.456	<.001	<.001	3	8
LSCC	ANKRD44 →	+0.549	+0.393	<.001	<.001	3	8
LSCC	LPXN →	+0.638	+0.412	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,647 associations by consensus.

ANGPTL6 vs DOCK2 — LSCC

Explore this scatter interactively →