Across TCGA cell cohorts, ANGPTL5 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANGPTL5-associated genes across cancer lineages are CNTNAP5, MS4A6E, and OR11A1. Each is linked with ANGPTL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANGPTL5-to-partner and partner-to-ANGPTL5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPTL5→partner) and Y-score (partner→ANGPTL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CNTNAP5 →	+0.285	+4.276	<.001	.007	3	1
BLOOD_Leukemia	MS4A6E →	+0.214	+4.551	<.001	.004	3	1
BLOOD_Leukemia	OR11A1 →	+0.015	+4.152	<.001	.009	3	1
BLOOD_Leukemia	OR14A2 →	+0.022	+5.060	<.001	.001	3	1
LARGE_INTESTINE	FGFBP2 →	+1.554	+3.254	<.001	.007	3	1
LARGE_INTESTINE	ECE2 →	+0.214	+2.791	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

ANGPTL5 survival (RNA) · tumor vs normal (RNA) · all ANGPTL5 data types