ANGPTL4

Across TCGA cell cohorts, ANGPTL4 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANGPTL4-associated genes across cancer lineages are LMNTD1, UTF1, and OR10W1. Each is linked with ANGPTL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANGPTL4-to-partner and partner-to-ANGPTL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LMNTD1 grouped by ANGPTL4-low versus ANGPTL4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPTL4→partner) and Y-score (partner→ANGPTL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LMNTD1 →	+0.186	+2.969	<.001	.007	3	1
LARGE_INTESTINE	UTF1 →	+0.015	+3.217	<.001	.006	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
LARGE_INTESTINE	LRRC3C →	+0.291	+3.099	<.001	.004	3	1
LARGE_INTESTINE	MAGEB1 →	+0.159	+2.878	.002	.009	3	1
LARGE_INTESTINE	CHAT →	+0.022	+3.103	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

LMNTD1 by ANGPTL4 expression — LARGE_INTESTINE

Explore this box plot interactively →