ANGPTL1

Across TCGA cell cohorts, ANGPTL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,532 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANGPTL1-associated GO terms across cancer lineages are Stress granule assembly, Cardiac muscle cell action potential, and Negative regulation of respiratory burst involved in inflammatory response. Each is linked with ANGPTL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANGPTL1-to-partner and partner-to-ANGPTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Stress granule assembly grouped by ANGPTL1-low versus ANGPTL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPTL1→partner) and Y-score (partner→ANGPTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Stress granule assembly →	+0.086	+0.075	.002	<.001	3	6
SKIN	Cardiac muscle cell action potential →	-0.100	-0.390	<.001	.004	3	6
URINARY_TRACT	Negative regulation of respiratory burst involved in inflammatory response →	+0.037	+0.036	.009	.008	3	6
URINARY_TRACT	Negative regulation of respiratory burst →	+0.037	+0.036	.009	.008	3	6
BLOOD_Lymphoma	Peptidyl-amino acid modification →	+0.022	+0.164	<.001	.001	3	5
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.060	+0.096	.001	.007	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,532 associations by consensus.

Stress granule assembly by ANGPTL1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →