ANGPT1

Across TCGA patient cohorts, ANGPT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,139 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ANGPT1-associated proteins across cancer lineages are CAVIN3, EHD2, and GGT5. Each is linked with ANGPT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANGPT1-to-partner and partner-to-ANGPT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANGPT1 versus CAVIN3 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPT1→partner) and Y-score (partner→ANGPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CAVIN3 →	+0.979	+0.724	<.001	<.001	3	8
BRCA	EHD2 →	+1.062	+0.788	<.001	<.001	3	8
OV	GGT5 →	+0.759	+0.998	<.001	.001	3	8
OV	TNS1 →	+0.707	+0.980	.005	.002	3	8
CCRCC	TNS2 →	+0.429	+1.023	<.001	<.001	3	8
OV	TNS2_S102 →	+1.118	+1.106	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,139 associations by consensus.

ANGPT1 vs CAVIN3 — BRCA

Explore this scatter interactively →