ANGEL1

Across TCGA patient cohorts, ANGEL1 RNA expression is significantly associated with the RNA expression of many other genes, with 20,670 significant associations in total. ACC shows the largest number of these associations.

The most reproducible ANGEL1-associated genes across cancer lineages are EP300, ALKBH1, and ZC3H14. Each is linked with ANGEL1 in more than 33 cancer types. Because this analysis shows association rather than direction, both ANGEL1-to-partner and partner-to-ANGEL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANGEL1 versus EP300 in DLBC, with a Pearson correlation of 0.75.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGEL1→partner) and Y-score (partner→ANGEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	EP300 →	+1.857	+0.845	<.001	<.001	3	34
ACC	ALKBH1 →	+1.001	+1.124	<.001	<.001	3	34
UVM	ZC3H14 →	+0.952	+0.993	<.001	<.001	3	34
DLBC	CHD8 →	+1.022	+0.845	<.001	<.001	3	34
DLBC	RBL2 →	+1.746	+0.853	<.001	<.001	3	34
DLBC	MED23 →	+1.187	+0.834	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,670 associations by consensus.

ANGEL1 vs EP300 — DLBC

Explore this scatter interactively →