ANGEL1

Across TCGA patient cohorts, ANGEL1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,675 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ANGEL1-associated genes across cancer lineages are ELMO3, FST, and ARHGEF3. Each is linked with ANGEL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANGEL1-to-partner and partner-to-ANGEL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANGEL1 versus ELMO3 in OV, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGEL1→partner) and Y-score (partner→ANGEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ELMO3 →	-0.752	-0.430	.007	.008	3	2
UCEC	FST →	+1.897	+0.608	.001	.002	3	2
UCEC	ARHGEF3 →	-1.227	-0.539	<.001	.003	3	2
UCEC	LINC02256 →	-1.417	-0.791	<.001	.005	3	2
UCEC	ADAMTS6 →	-1.408	-0.510	.007	.006	3	2
LUAD	PPFIA3 →	+0.794	+0.321	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,675 associations by consensus.

ANGEL1 vs ELMO3 — OV

Explore this scatter interactively →