ANGEL1

Across TCGA cell cohorts, ANGEL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,102 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ANGEL1-associated GO terms across cancer lineages are Nuclear export, RNA catabolic process, and Negative regulation of chromosome condensation. Each is linked with ANGEL1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ANGEL1-to-partner and partner-to-ANGEL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by ANGEL1-low versus ANGEL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGEL1→partner) and Y-score (partner→ANGEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nuclear export →	+0.098	+1.341	<.001	<.001	3	16
BONE	RNA catabolic process →	+0.081	+1.034	<.001	<.001	3	16
OVARY	Negative regulation of chromosome condensation →	+0.160	+0.754	<.001	<.001	3	16
KIDNEY	Promoter clearance during DNA-templated transcription →	+0.141	+0.967	.001	.003	3	16
KIDNEY	RNA polymerase II promoter clearance →	+0.141	+0.967	.001	.003	3	16
BONE	Microtubule nucleation →	+0.145	+1.132	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,102 associations by consensus.

Nuclear export by ANGEL1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →