Across TCGA patient cohorts, ANAPC7 mutation is significantly associated with the RNA expression of many other genes, with 335 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANAPC7-associated genes across cancer lineages are HSFY1, RPL35AP35, and RNA5SP161. Each is linked with ANAPC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANAPC7-to-partner and partner-to-ANAPC7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC7→partner) and Y-score (partner→ANAPC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSFY1 →	+0.009	+5.571	<.001	.002	3	2
SKCM	RPL35AP35 →	+0.118	+2.740	.003	.002	3	2
UCEC	RNA5SP161 →	+1.282	+2.429	<.001	.004	3	2
UCEC	RNA5SP442 →	+0.485	+2.866	<.001	.002	3	2
UCEC	SNRPEP7 →	+0.265	+2.403	<.001	.008	3	2
UCEC	RPL23AP19 →	+0.498	+3.643	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 335 associations by consensus.

Exploration

ANAPC7 survival (RNA) · tumor vs normal (RNA) · all ANAPC7 data types