Across TCGA patient cohorts, ANAPC7 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANAPC7-associated genes across cancer lineages are Notch1, Rab25, and IGFBP2. Each is linked with ANAPC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANAPC7-to-partner and partner-to-ANAPC7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC7→partner) and Y-score (partner→ANAPC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.207	+3.009	.007	.019	3	1
UCEC	Rab25 →	-0.500	-3.000	.006	.036	3	1
SKCM	IGFBP2 →	-0.585	-3.000	.046	.036	2	2
SKCM	Smad4 →	+0.148	+3.000	.022	.036	3	1
UCEC	p27_pT157 →	-0.070	-3.169	.027	.020	2	1
UCEC	4E-BP1 →	+0.511	+3.169	<.001	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

ANAPC7 survival (RNA) · tumor vs normal (RNA) · all ANAPC7 data types