Across TCGA cell cohorts, ANAPC7 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ANAPC7-associated genes across cancer lineages are ZAN, FOXR1, and PRAMEF17. Each is linked with ANAPC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANAPC7-to-partner and partner-to-ANAPC7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC7→partner) and Y-score (partner→ANAPC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ZAN →	+0.004	+4.369	<.001	.008	3	1
SOFT_TISSUE	FOXR1 →	+0.132	+4.222	<.001	.007	3	1
SOFT_TISSUE	PRAMEF17 →	+0.014	+4.369	<.001	.008	3	1
SOFT_TISSUE	DPRX →	+0.049	+4.369	<.001	.008	3	1
SOFT_TISSUE	IFNA14 →	+0.024	+4.369	<.001	.008	3	1
SOFT_TISSUE	PRAMEF18 →	+0.022	+5.515	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

ANAPC7 survival (RNA) · tumor vs normal (RNA) · all ANAPC7 data types