ANAPC5

Across TCGA patient cohorts, ANAPC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,922 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANAPC5-associated proteins across cancer lineages are SRSF9, SART3, and CPSF6. Each is linked with ANAPC5 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANAPC5-to-partner and partner-to-ANAPC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANAPC5 versus SRSF9 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC5→partner) and Y-score (partner→ANAPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRSF9 →	+0.393	+0.345	<.001	<.001	3	8
OV	SART3 →	+0.407	+0.449	<.001	<.001	3	8
LSCC	CPSF6 →	+0.295	+0.394	<.001	<.001	3	6
LSCC	EFTUD2 →	+0.181	+0.381	<.001	<.001	3	6
OV	MTREX →	+0.276	+0.402	<.001	<.001	3	6
GBM	USP39 →	+0.300	+0.290	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,922 associations by consensus.

ANAPC5 vs SRSF9 — LSCC

Explore this scatter interactively →