ANAPC5

Across TCGA patient cohorts, ANAPC5 protein abundance is significantly associated with the RNA expression of many other genes, with 7,313 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANAPC5-associated genes across cancer lineages are EXO1, TIMELESS, and BRCA1. Each is linked with ANAPC5 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANAPC5-to-partner and partner-to-ANAPC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANAPC5 versus EXO1 in LSCC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC5→partner) and Y-score (partner→ANAPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EXO1 →	+0.928	+0.182	<.001	<.001	3	6
GBM	TIMELESS →	+0.844	+0.150	<.001	.001	3	6
LSCC	BRCA1 →	+0.982	+0.195	<.001	<.001	3	6
GBM	CHAF1B →	+0.844	+0.136	<.001	.002	3	6
GBM	POLQ →	+0.966	+0.122	<.001	.008	3	6
GBM	MYBL2 →	+1.344	+0.156	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,313 associations by consensus.

ANAPC5 vs EXO1 — LSCC

Explore this scatter interactively →