ANAPC5

Across TCGA cell cohorts, ANAPC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,095 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANAPC5-associated GO terms across cancer lineages are Signal transduction in response to DNA damage, Rostrocaudal neural tube patterning, and DNA integrity checkpoint signaling. Each is linked with ANAPC5 in more than 14 cancer types. Because this analysis shows association rather than direction, both ANAPC5-to-partner and partner-to-ANAPC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Signal transduction in response to DNA damage grouped by ANAPC5-low versus ANAPC5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC5→partner) and Y-score (partner→ANAPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Signal transduction in response to DNA damage →	+0.075	+0.508	.004	.001	3	15
BONE	Rostrocaudal neural tube patterning →	+0.145	+0.724	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA integrity checkpoint signaling →	+0.094	+0.977	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Defense response to bacterium →	-0.141	-0.791	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA damage checkpoint signaling →	+0.094	+0.872	.003	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA integrity checkpoint signaling →	+0.095	+0.938	.002	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,095 associations by consensus.

Signal transduction in response to DNA damage by ANAPC5 expression — OESOPHAGUS

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