ANAPC2

Across TCGA patient cohorts, ANAPC2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,601 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANAPC2-associated genes across cancer lineages are PMPCA, TMEM97, and EXOSC2. Each is linked with ANAPC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANAPC2-to-partner and partner-to-ANAPC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANAPC2 versus PMPCA in OV, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC2→partner) and Y-score (partner→ANAPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PMPCA →	+0.458	+0.219	.006	.005	3	4
LSCC	TMEM97 →	+0.799	+0.119	<.001	.006	3	4
GBM	EXOSC2 →	+0.445	+0.244	<.001	<.001	3	3
GBM	GTF3C4 →	+0.548	+0.271	<.001	<.001	3	3
GBM	RRAS →	-0.679	-0.223	<.001	<.001	3	3
GBM	TEX10 →	+0.524	+0.232	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,601 associations by consensus.

ANAPC2 vs PMPCA — OV

Explore this scatter interactively →