ANAPC2

Across TCGA cell cohorts, ANAPC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,819 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANAPC2-associated GO terms across cancer lineages are CTP salvage, Regulation of mRNA splicing, via spliceosome, and Establishment of RNA localization. Each is linked with ANAPC2 in more than 17 cancer types. Because this analysis shows association rather than direction, both ANAPC2-to-partner and partner-to-ANAPC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTP salvage grouped by ANAPC2-low versus ANAPC2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC2→partner) and Y-score (partner→ANAPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CTP salvage →	+0.186	+1.262	<.001	<.001	3	18
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.113	+1.206	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.112	+1.531	<.001	<.001	3	18
BONE	RNA export from nucleus →	+0.111	+1.015	<.001	<.001	3	18
SOFT_TISSUE	Regulation of RNA splicing →	+0.096	+1.093	<.001	<.001	3	18
OESOPHAGUS	mRNA transport →	+0.115	+1.252	.006	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,819 associations by consensus.

CTP salvage by ANAPC2 expression — URINARY_TRACT

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