ANAPC1P5

Across TCGA patient cohorts, ANAPC1P5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,564 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ANAPC1P5-associated GO terms across cancer lineages are Regulation of cell cycle G2/M phase transition, Centrosome duplication, and Regulation of telomerase activity. Each is linked with ANAPC1P5 in more than 13 cancer types. Because this analysis shows association rather than direction, both ANAPC1P5-to-partner and partner-to-ANAPC1P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell cycle G2/M phase transition grouped by ANAPC1P5-low versus ANAPC1P5-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC1P5→partner) and Y-score (partner→ANAPC1P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of cell cycle G2/M phase transition →	+0.053	+0.113	.001	.002	3	14
STAD	Centrosome duplication →	+0.048	+0.071	<.001	<.001	3	12
STAD	Regulation of telomerase activity →	+0.046	+0.063	<.001	<.001	3	12
STAD	DNA replication →	+0.051	+0.072	<.001	<.001	3	12
STAD	DNA-templated DNA replication →	+0.051	+0.064	<.001	<.001	3	12
ESCA	Response to ionizing radiation →	+0.058	+0.128	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,564 associations by consensus.

Regulation of cell cycle G2/M phase transition by ANAPC1P5 expression — ESCA

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