ANAPC1P3

Across TCGA pan-cancer cohorts, ANAPC1P3 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated ANAPC1P3 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ANAPC1P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANAPC1P3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LAML show a favorable association.

HNSC, LUSC, and KIRP are the cancer types where ANAPC1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.467	0.707	.005	48	view →
LUSC	DFS	Tertile	All	0.488	0.665	.007	27	view →
KIRP	DFS	Tertile	All	0.706	0.866	.008	24	view →
COAD	DFS	Tertile	III,IV	0.123	0.497	.016	21	view →
GBM	DFS	Tertile	All	0.220	0.305	.009	18	view →
SKCM	DFS	Tertile	II,III,IV	0.500	0.245	.026	12	view →
LIHC	OS	Tertile	III,IV	0.412	0.770	.006	9	view →
READ	OS	Tertile	II,III,IV	0.603	0.925	.012	9	view →
LAML	DFS	Quartile	All	0.627	0.312	.044	4	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

ANAPC1P3–HNSC (DFS)

Open the HNSC breakdown →