ANAPC1P1

Across TCGA pan-cancer cohorts, ANAPC1P1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ANAPC1P1 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ANAPC1P1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ANAPC1P1 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

COAD, LUAD, and ESCA are the cancer types where ANAPC1P1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	III,IV	0.056	0.783	<.001	24	view →
LUAD	DFS	Median	IV	0.342	0.893	<.001	22	view →
ESCA	DFS	Median	All	0.080	0.533	<.001	18	view →
LUSC	DFS	Median	II,III,IV	0.198	0.594	.025	3	view →
SKCM	DFS	Median	II,III,IV	0.938	0.662	.009	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ANAPC1P1–COAD (OS)

Open the COAD breakdown →