ANAPC16

Across TCGA pan-cancer cohorts, ANAPC16 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ANAPC16 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ANAPC16 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ANAPC16 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, HNSC, and LSCC are the cancer types where ANAPC16 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.908	.012	28	view →
HNSC	DFS	Quartile	IV	0.555	0.893	.017	11	view →
LSCC	DFS	Median	III,IV	0.449	0.894	.017	5	view →
PDAC	OS	Quartile	III,IV	0.975	0.407	.008	3	view →
GBM	OS	Tertile	All	0.801	0.940	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ANAPC16–UCEC (OS)

Open the UCEC breakdown →