ANAPC16

Across TCGA patient cohorts, ANAPC16 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANAPC16-associated genes across cancer lineages are RNU6-1174P, RNU7-19P, and DNAJB8-AS1. Each is linked with ANAPC16 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANAPC16-to-partner and partner-to-ANAPC16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1174P grouped by ANAPC16-low versus ANAPC16-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC16→partner) and Y-score (partner→ANAPC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1174P →	+0.430	+5.771	<.001	.003	3	2
SKCM	RNU7-19P →	+0.736	+5.513	<.001	.004	3	1
SKCM	DNAJB8-AS1 →	+0.030	+5.224	<.001	.007	3	1
LUAD	OPN1LW →	+0.153	+5.712	<.001	.003	3	1
LUAD	RNU6-662P →	+0.530	+5.217	<.001	.007	3	1
LUAD	RNA5SP23 →	+0.382	+5.554	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

RNU6-1174P by ANAPC16 expression — SKCM

Explore this box plot interactively →