ANAPC15

Across TCGA patient cohorts, ANAPC15 mutation is significantly associated with the RNA expression of many other genes, with 292 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANAPC15-associated genes across cancer lineages are ANAPC15P2, RN7SKP44, and OR10T1P. Each is linked with ANAPC15 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANAPC15-to-partner and partner-to-ANAPC15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANAPC15P2 grouped by ANAPC15-low versus ANAPC15-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC15→partner) and Y-score (partner→ANAPC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	ANAPC15P2 →	+0.135	+5.103	<.001	.008	3	2
CESC	RN7SKP44 →	+0.222	+5.010	<.001	.009	3	1
CESC	OR10T1P →	+0.056	+5.418	<.001	.005	3	1
CESC	SLC44A3P1 →	+0.033	+5.306	<.001	.006	3	1
UCEC	IGHV3OR16-6 →	+0.543	+3.397	.004	<.001	3	1
UCEC	LINC01050 →	+0.282	+2.566	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 292 associations by consensus.

ANAPC15P2 by ANAPC15 expression — CESC

Explore this box plot interactively →