ANAPC15

Across TCGA cell cohorts, ANAPC15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,064 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANAPC15-associated GO terms across cancer lineages are Positive regulation of attachment of mitotic spindle microtubules to kinetochore, Regulation of attachment of mitotic spindle microtubules to kinetochore, and Mitotic spindle elongation. Each is linked with ANAPC15 in more than 14 cancer types. Because this analysis shows association rather than direction, both ANAPC15-to-partner and partner-to-ANAPC15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of attachment of mitotic spindle microtubules to kinetochore grouped by ANAPC15-low versus ANAPC15-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC15→partner) and Y-score (partner→ANAPC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.150	+0.777	<.001	<.001	3	15
SOFT_TISSUE	Regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.130	+0.829	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Mitotic spindle elongation →	+0.265	+1.342	.005	.009	2	13
OVARY	Spindle elongation →	+0.200	+0.840	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Mitotic spindle midzone assembly →	+0.265	+1.342	.005	.009	2	13
BLOOD_Lymphoma	Positive regulation of chromosome condensation →	+0.169	+1.085	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,064 associations by consensus.

Positive regulation of attachment of mitotic spindle microtubules to kinetochore by ANAPC15 expression — SOFT_TISSUE

Explore this box plot interactively →