ANAPC13

Across TCGA patient cohorts, ANAPC13 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ANAPC13-associated genes across cancer lineages are SULT1C3, HBG1, and RNU4-65P. Each is linked with ANAPC13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANAPC13-to-partner and partner-to-ANAPC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SULT1C3 grouped by ANAPC13-low versus ANAPC13-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC13→partner) and Y-score (partner→ANAPC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SULT1C3 →	+0.147	+5.159	.001	.007	3	1
SKCM	HBG1 →	+0.100	+5.680	<.001	.003	3	1
SKCM	RNU4-65P →	+0.432	+6.328	<.001	.001	3	1
SKCM	RNA5SP38 →	+0.661	+5.867	<.001	.003	3	1
SKCM	RN7SKP192 →	+0.248	+5.159	<.001	.007	3	1
SKCM	MIPEPP2 →	+0.034	+5.436	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

SULT1C3 by ANAPC13 expression — SKCM

Explore this box plot interactively →