ANAPC11

Across TCGA patient cohorts, ANAPC11 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,372 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANAPC11-associated proteins across cancer lineages are DNMT1_S714, MCM2, and MCM3. Each is linked with ANAPC11 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANAPC11-to-partner and partner-to-ANAPC11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANAPC11 versus DNMT1_S714 in LUAD, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC11→partner) and Y-score (partner→ANAPC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DNMT1_S714 →	+0.636	+0.442	<.001	<.001	3	6
GBM	MCM2 →	+0.593	+0.308	<.001	.001	3	6
LSCC	MCM3 →	+0.663	+0.685	<.001	<.001	3	6
OV	MRPL53 →	+0.440	+0.575	<.001	<.001	3	5
GBM	NCAPD2 →	+0.562	+0.332	<.001	<.001	3	5
GBM	NUDT1 →	+0.310	+0.248	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,372 associations by consensus.

ANAPC11 vs DNMT1_S714 — LUAD

Explore this scatter interactively →