ANAPC11

Across TCGA patient cohorts, ANAPC11 mutation is significantly associated with the RNA expression of many other genes, with 204 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANAPC11-associated genes across cancer lineages are RNU6-1210P, NTAN1P1, and CTAGE6. Each is linked with ANAPC11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANAPC11-to-partner and partner-to-ANAPC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1210P grouped by ANAPC11-low versus ANAPC11-high in KIRC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC11→partner) and Y-score (partner→ANAPC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	RNU6-1210P →	+0.224	+8.025	<.001	.007	3	2
UCEC	NTAN1P1 →	+0.099	+3.715	.008	.002	3	1
UCEC	CTAGE6 →	+0.053	+2.578	.002	.006	3	1
UCEC	RPL23AP90 →	+0.546	+2.954	<.001	.003	3	1
UCEC	MIR6508 →	+0.417	+3.260	<.001	.002	3	1
UCEC	RPS29P32 →	+0.632	+3.014	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 204 associations by consensus.

RNU6-1210P by ANAPC11 expression — KIRC

Explore this box plot interactively →