ANAPC11

Across TCGA cell cohorts, ANAPC11 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,262 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ANAPC11-associated GO terms across cancer lineages are Aldehyde biosynthetic process, Respiratory burst after phagocytosis, and Regulation of transcription from RNA polymerase II promoter by glucose. Each is linked with ANAPC11 in more than 8 cancer types. Because this analysis shows association rather than direction, both ANAPC11-to-partner and partner-to-ANAPC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aldehyde biosynthetic process grouped by ANAPC11-low versus ANAPC11-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC11→partner) and Y-score (partner→ANAPC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Aldehyde biosynthetic process →	+0.115	+0.681	.005	.007	2	9
SKIN	Respiratory burst after phagocytosis →	+0.168	+0.641	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription from RNA polymerase II promoter by glucose →	-0.188	-0.649	.004	.007	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of transcription from RNA polymerase II promoter by glucose →	-0.188	-0.649	.004	.007	3	8
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication →	+0.172	+0.858	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Protein-DNA covalent cross-linking repair →	+0.101	+0.976	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,262 associations by consensus.

Aldehyde biosynthetic process by ANAPC11 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →